Liver inflammation, injury, and hepatic cell death are caused by external agents (viruses, bacteria, drugs, alcohol, etc.) along with the genetic susceptibility of an individual.Persistent activation of the fibrogenic response in cells leads to liver fibrosis which in turn progresses to cirrhosis and cancer.The dysregulation of the immune system ge
The article discusses the linguistic means of implementing comic in order to convey negative evaluativeness in the English-language online movie reviews.The various comic techniques are a rich linguistic arsenal for showing authors criticism.The pragmatic motivation of satirical and ironic texts is the introduction of new, different from the existi
In this work, a robust optimisation approach has been developed to handle the uncertainty in integrated planning, scheduling and dynamic optimisation for continuous manufacturing processes.We first propose an integrated optimisation model for multi-product continuous processes.A robust optimisation approach is then introduced to address the process
In this study, we aim to analyse the position of cultural Islam in Northern European countries.To this end, we examine publications in major print media.Content analysis of relevant publications gives a detailed picture of narratives produced in mass consciousness as a reaction to the presence of Islam at the local and regional level and makes it p
Sickle cell disease (SCD) is caused by a single-point mutation, and the ensuing deoxygenation-induced polymerization of sickle hemoglobin (HbS), and reduction in bioavailability of vascular nitric oxide (NO), contribute to the pathogenesis of the disease.In a proof-of-concept study, we successfully incorporated nitrate ester groups onto two previou